Yes and No. To enjoy full speed of Crossfire mod inverter is needed, however, if you're not comfortable doing so you can simply lower the baudrate to 115,200. Downside is latency will increase.
"The regular update rate for CRSF between OpenTX and Crossfire is 250Hz (4ms). Using the lower baudrate the update rate is reduced to 62.5Hz (16ms). Because of this we recommend to fix it properly in hardware if you have the soldering skills or ask FrSky for support on fixing the hardware".
Taranis mod inverter installation:
https://blog.seidel-philipp.de/fixed-inverter-mod-for-tbs-crossfire-and-frsky-qx7/